Sustalad (Sustanon) Driada Medical 250 mg/ml 10ml Vials

Sustalad 250 mg/ml (Sustanon) 10ml Vials

Testosterone, the primary sex hormone in both men and women, plays a crucial role in the development of reproductive tissues, as well as secondary sexual characteristics such as muscle and bone mass and body hair. It is essential for overall health, well-being, and the prevention of conditions such as osteoporosis. Testosterone exhibits significant anabolic properties, promoting muscle growth, protein synthesis, and glycogen replenishment. It is widely used in medical treatments for gender dysphoria, male hypogonadism, and certain types of breast cancer. Although testosterone is renowned in the athletic world for its muscle-building effects, it also serves as a vital hormone for various physiological processes.

Mechanism of Action

Testosterone binds to androgen receptors and acts as a precursor to dihydrotestosterone (DHT), a biologically active androgen formed through the conversion of testosterone by the enzyme 5α-reductase. DHT exhibits a higher affinity for androgen receptors. These hormone-receptor interactions initiate changes in gene expression, leading to androgenic effects. Aromatase can convert testosterone to estrogen, a process known as aromatization. Estrogen, rather than testosterone itself, regulates the hypothalamic-pituitary-testicular axis and suppresses endogenous testosterone production when exogenous testosterone is administered.

Medical Use

Testosterone is classified as an essential medicine by the World Health Organization, underscoring its critical role in healthcare. It is used in hormone replacement therapy (HRT) and testosterone replacement therapy (TRT) for conditions such as gender dysphoria, male hypogonadism, and some types of breast cancer. Age-related testosterone decline necessitates HRT or TRT to maintain optimal health and quality of life. Inadequate testosterone levels in men can lead to frailty, bone loss, and other abnormalities. Testosterone also affects cognitive functions, including mood, spatial ability, attention, memory, and the risk of cognitive decline and dementia.

Testosterone for Seniors

Men over 35 who experience a decline in well-being are often advised to undergo blood testosterone testing. If levels fall below 12 nmol/L, hormone replacement therapy is recommended. This approach offers several benefits, including improved body composition with increased muscle mass and decreased fat, rejuvenating effects, and improved sexual function. Monitoring lipid profiles, blood parameters, and hormone levels during therapy is crucial. For individuals seeking to conceive, additional gonadotropin therapy may be necessary, as testosterone therapy suppresses natural gonadotropin production.

Testosterone in Sport

Testosterone is widely favored by athletes and bodybuilders due to its ability to improve muscle mass and strength. It exhibits both anabolic and androgenic effects, binding to androgen receptors and activating gene expression to stimulate muscle growth. Testosterone also facilitates regeneration processes, improves oxygen capacity and nitric oxide production, and positively impacts endurance and exercise performance. Typical doses in sports range from 250 to 500 mg per week, with adjustments based on individual factors such as body weight and response. Aromatase inhibitors are often used to mitigate estrogenic side effects.

Dosages

• Beginner: 250 mg per week
• Average dosage: 300-750 mg per week
• High dosage: 750+ mg per week

Effects

• Increased muscle mass
• Development of male sexual characteristics
• Improved spermatogenesis and male behavior
• Fat burning
• Increased strength
• High libido
• Reduction of blood cholesterol levels
• Reducing the risk of cardiac ischemia and coronary heart disease
• Stimulation of erythropoiesis and redistribution of subcutaneous adipose tissue
• Modulation of nitrogen and phosphorus metabolism

Side Effects

• Increased blood pressure
• High sexual behavior
• Hemoconcentration (blood clotting)
• Potential for blood clots in arterial and venous vessels
• Water retention (edema)
• Masculinization
• Aggression, agitation, irritability
• Alopecia (baldness of the scalp)
• Acne
• Insomnia (rare)

Profile

• Half-life: 7-15 days
• Frequency of injections: 4-7 days

Pharmaceutical Form

• Oily solution for intramuscular injection.

Contraindications

• Pregnancy
• Known or suspected prostate or breast cancer
• Breastfeeding
• Hypersensitivity to the active substance or to any of the excipients

Conservation

• Do not use after the expiration date
• Store between 8ºC and 30ºC
• Avoid freezing
• Protect from light