CJC-1295 with DAC Driada Medical 2 mg

CJC-1295 with 2 mg DAC

CJC-1295 is a peptide hormone composed of 30 amino acids. It acts as an analogue of somatolibtin, a natural stimulator of growth hormone secretion. CJC-1295 acts on the nucleus of the anterior pituitary gland, stimulating the release of growth hormone. The substance binds to GHRH receptors, which are part of the G-protein-coupled receptor group. The version of CJC-1295 with DAC (Drug Affinity Complex) binds to plasma proteins, such as albumin, ensuring a prolonged duration of action compared to the version without DAC, which lasts only 30 minutes.

GHRH Group:

GHRH stands for Growth Hormone Releasing Hormone or Somatolibrin. It is a peptide hormone composed of 44 amino acids and is produced in the hypothalamus. GHRH stimulates the pulsatile release of growth hormone from the anterior pituitary gland, contributing to slow-wave sleep.

Mechanism of action:

Somatoliberin is released from arch neurons and transported to the anterior pituitary gland, where it stimulates the release of growth hormone by binding to specific receptors. It counteracts the action of somatostatin, a hormone that inhibits growth hormone secretion. The pulsatile release of somatoliberin and somatostatin leads to pulsatile secretion of growth hormone. GHRH peptides work when somatostatin levels are low or its activity is minimal, typically during natural releases or after growth hormone injections. GHRH peptides increase endogenous growth hormone levels, leading to positive effects such as fat loss, increased muscle mass, improved cholesterol levels, and enhanced healing.

Purpose of use:

The use of GHRH peptides, including CJC-1295, offers benefits such as increased fat loss, improved muscle gain, reduced cholesterol and triglyceride levels, and improved recovery from injuries. These peptides do not negatively affect blood sugar levels and help establish a natural pulsatile pattern of growth hormone surges in the blood.

Effects:

• Sustained increase in growth hormone and IGF-1 levels
• Reduction of visceral adipose tissue
• Reduction of total cholesterol and triglyceride levels
• Increased muscle mass

Side effects:

• Temporary redness of the face and pain at the injection site
• Artialgia (joint pain)
• Myalgia (muscle pain)

Tesamorelin, GRF (1-44):

Tesamorelin is a growth hormone stimulant with a longer half-life than other GHRH peptides. It contains all 44 amino acids of somatolibtin and is effective for approximately 4–5 hours. It is commonly used in medical practice as a stimulator of growth hormone secretion.

Sermorelin, GRF (1-29):

Sermorelin is a peptide composed of the first 29 amino acids of somatolibtin. It has a short half-life of about 2 hours, but can significantly increase growth hormone levels when combined with GHRP peptides.

Mod GRF (1-29):

Mod GRF(1-29) is similar to sermorelin but has a longer half-life of approximately 30 minutes. It is also known as modified GRF(1-29) or Mod GRF(1-29).

CJC-1295 with DAC:

CJC-1295 with DAC is derived from Mod GRF (1-29) and has an even longer half-life, lasting several days. This peptide offers a prolonged period of efficacy and maintains the pulsatile nature of growth hormone release.

Application scheme:

GHRH peptides typically have short half-lives, requiring frequent injections, often 3 to 4 times a day. CJC-1295 DAC, with its longer duration of action, can be injected twice a week. GHRH peptides are often combined with GHRP peptides such as GHRP-2, GHRP-6, hexarelin, or ipamorelin for a synergistic effect.

How to prepare a solution:

To prepare a solution for injection, a diluent is added to a vial containing the lyophilized powder. Care must be taken to avoid direct injection into the powder. The vial is gently shaken until the powder dissolves, resulting in a clear, ready-to-use liquid. Peptides should not be mixed in the same syringe to avoid degradation.

Application:

The injection can be administered subcutaneously or intramuscularly, depending on personal preference.

Conservation:

The prepared solution can be stored in the refrigerator at 2-8°C for approximately 21 days. The shelf life may be increased if bacteriostatic water is used as a diluent.