Cypilos (Testosterone Cypionate) Driada Medical 250 mg/ml

Testosterone is the primary sex hormone in men and plays a crucial role in the development of reproductive tissues in both males and females. It promotes the growth of secondary sexual characteristics, such as increased muscle and bone mass, hair growth, and prostate development in males. Testosterone also contributes to overall health, well-being, and the prevention of osteoporosis in both sexes. Inadequate testosterone levels in men can lead to abnormalities, including bone fragility and loss of bone mass. Although testosterone is widely known for its anabolic properties, such as increased muscle mass and protein synthesis, it is also essential for various physiological processes in the body. Testosterone-based drugs are used not only by athletes during steroid cycles, but also by elderly individuals with age-related hypogonadism as a form of hormone replacement therapy.

Mechanism of action

Testosterone binds to androgen receptors and serves as a precursor to dihydrotestosterone (DHT), a biologically active androgen. DHT is formed when testosterone interacts with the enzyme 5α-reductase. DHT has a higher binding affinity for androgen receptors than testosterone. When these hormones bind to the receptors, they induce structural changes that trigger signal transmission to the cell nucleus, where androgenic effects are achieved by altering the activity of specific DNA genes. Testosterone can also undergo aromatization, converting to estrogen through the action of aromatase. Estrogen, rather than testosterone itself, primarily triggers feedback through the hypothalamic-pituitary-testosterone axis, suppressing endogenous testosterone secretion when exogenous drugs are administered.

Medical use

Testosterone is included in the World Health Organization’s List of Essential Medicines for its critical role in several medical applications. It is used to treat conditions such as gender dysphoria, male hypogonadism, and certain types of breast cancer. Hormone replacement therapy (HRT), or testosterone replacement therapy (TRT), is used to maintain testosterone levels within the normal range, particularly in aging men. Low testosterone levels have been associated with cognitive decline and certain health problems, making testosterone treatment useful for adult men with age-related testosterone deficiency and sexual dysfunction. Monitoring lipid profiles, clinical blood parameters, and hormone levels, including estradiol and prolactin, is essential during testosterone therapy. Men wishing to conceive while undergoing HRT may require specialized gonadotropin therapy.

Testosterone in sports

One of the main benefits of testosterone in sports is its ability to increase muscle mass and strength. It has both anabolic and androgenic effects. Androgens enter cells and interact with androgen receptor (AR) proteins, resulting in their activation. This activation allows the AR to enter the nucleus and bind to DNA, influencing gene expression. Testosterone is also associated with water retention, joint health, pain relief, and promoting the body’s regeneration processes. It increases overall tone, motivation to exercise, and blood oxygen capacity, resulting in improved performance during training. In sports, testosterone is commonly used in dosages ranging from 250 to 500 mg per week, which can be adjusted based on the athlete’s body weight. The cycle duration is typically 8–10 weeks, followed by post-cycle therapy (PCT) after a 2–3 week break. Monitoring estradiol levels and using aromatase inhibitors can help mitigate the estrogenic side effects caused by aromatization. It’s important to consult with a healthcare professional when choosing a dosage and carefully follow your doctor’s instructions.

Dosages

• Beginner: 250 mg per week
• Average dosage: 300-750 mg per week
• High dosage: 750+ mg per week

Effects

• Increased muscle mass
• Development of male genitalia and secondary sexual characteristics
• It promotes spermatogenesis and male behavior (sexuality, aggression, determination)
• Burn fat
• Increased strength
• Increased libido
• Reduction of blood cholesterol levels
• Reduction of the risk of cardiac ischemia and coronary heart disease
• Stimulation of erythropoiesis and male distribution of subcutaneous adipose tissue
• It influences nitrogen and phosphorus metabolism

Side effects

• Increased blood pressure
• Increased sexual behavior
• Hemoconcentration (blood clotting)
• Possible formation of blood clots in the arterial and venous vessels
• Water retention (edema)
• Masculinization
• Aggression, agitation, irritability
• Alopecia (baldness of the scalp)
• acne
• Insomnia (rare)

Profile

• Half-life: 6-8 days
• Frequency of injections: Every 5-7 days
• Pharmaceutical form

Oily solution for intramuscular injection
Contraindications

Pregnancy
Known or suspected carcinoma of the prostate or breast
Breastfeeding
Hypersensitivity to the active substance or to any of the excipients
Storage

Do not use after the expiry date.
Store between 8ºC and 30ºC.
Do not freeze.
Protect from light.