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HCG 5000 1ml SuperHuman Pharma
Original price was: € 65,00.€ 55,00Current price is: € 55,00.
HCG 2000iu (Human Chorionic Gonadotropin) Driada Medical
€ 40,00
- Active ingredient: Human chorionic gonadotropin
- Type: Peptide hormone
- Packaging: 2000iu+water/vial
- Form: Injections
Description
HCG 2000iu (Human Chorionic Gonadotropin)
Human chorionic gonadotropin (HCG) is a polypeptide hormone composed of an alpha subunit similar to those found in luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH), and a beta subunit with a distinctive amino acid sequence. Consequently, HCG exerts LH-like effects in activating the production of gonadal steroid hormones, such as androgens and progesterone, influencing the development of male secondary sexual characteristics and regulating the normal menstrual cycle in women. However, its FSH activity is weak. During pregnancy, it supports the corpus luteum.
HCG, along with other gonadotropins, is naturally synthesized in the body and does not cause allergic reactions because it is not a xenobiotic. Human chorionic gonadotropin is produced by the placenta during pregnancy, excreted in the urine, and then extracted and purified for pharmaceutical purposes. It is an FDA-approved drug with proven efficacy.
Purpose of use
There are several important reasons for using HCG. Let’s focus on one that’s of particular interest to athletes and those undergoing testosterone replacement therapy (TRT). During a steroid or TRT cycle, exogenous testosterone suppresses the release of LH from the brain, leading to the cessation of the hypothalamic-pituitary-gonadal (HPTA) axis and the testes no longer receiving LH. This phenomenon, commonly known as “shutdown” or “HPTA suppression,” leads to testicular atrophy.
Over time, men may experience testicular shrinkage and persistent discomfort, accompanied by a significant reduction in sperm production. The duration of this process varies among individuals, with younger men often showing greater resilience than their older peers. While this is believed to be related to the number of receptors on Leydig cells, further research is needed to establish conclusive evidence.
In the body, gonadotropin levels are regulated through a feedback mechanism in the hypothalamic-pituitary-testicular axis. Gonadotropins are normally produced in the pituitary gland and stimulate testicular function. However, their deficiency leads to testicular atrophy. To prevent testicular atrophy, it is essential to support testicular function during menstruation or TRT, and HCG treatment plays an important role in achieving this goal.
Suppression of luteinizing hormone, which normally maintains normal testicular function, causes a 90% decrease in Leydig cell volume and a 98% decrease in endogenous testosterone secretion. However, because Leydig cells constitute only about 5% of testicular mass, testicular size does not accurately reflect the level of suppression. Despite minimal changes in testicular volume (only 5%), significant suppression of Leydig cell function can occur.
How to Use
There are various HCG protocols, but the following are considered optimal as they preserve testicular function and facilitate the most complete recovery after an anabolic steroid (AAS) cycle:
During long cycles of several months, HCG is used continuously, generally administered for 3-5 weeks followed by a 1-2 week break to avoid desensitization.
If HCG was not used during the cycle, it should be included in post-cycle therapy (PCT), but only at the beginning of PCT. The recommended protocol, supported by clinical studies and by William Llewellyn, suggests using HCG at a dose of 2000 IU every other day for 20 days to reboot the hypothalamic-pituitary-testicular axis. However, high doses (2000-5000 IU) should not be used for more than 20 days.
For people who inject testosterone once a week, a common protocol involves using 250 IU of HCG two days before and one day before the next testosterone injection. The theory behind this approach is to bridge the gap between testosterone injections by increasing natural production through HCG stimulation when serum testosterone levels approach their half-life.
It’s worth noting that large amounts of hCG can desensitize the Leydig cell receptors. According to Michael Scally, MD, and studies, testicular desensitization does not occur if the dose does not exceed 500 IU per injection and hCG is administered less than three times a week.
Furthermore, high doses of HCG can cause a rapid increase in estrogen levels. Therefore, to prevent this, aromatase inhibitors are not effective, as intratesticular aromatization can still occur. Alternatively, tamoxifen can be used, or the weekly HCG dose can be divided into smaller doses.
Effects
- Increased endogenous testosterone levels
- Increased sperm production
- Increased libido and mood
- Restoring fertility
- Preservation of testicular activity during the cycle
- Possibility of restoring your own testosterone production and fertility after prolonged steroid abuse
Side Effects
- Mild swelling
- Stomach or pelvic pain
- Less common or rare:
- Severe abdominal or stomach pain
- Moderate to severe swelling
- Decreased amount of urine
- Feeling of indigestion
- Severe nausea, vomiting, or diarrhea
- Severe pelvic pain
- Shortness of breath
- Swelling of the feet or lower legs
Drug Profile
- The half-life of HCG is several hours, but its effects last 5 to 6 days, gradually decreasing.
- Frequency of intake: Once every 3-7 days
How to Prepare a Solution
To prepare an injectable HCG solution, take a syringe containing a diluent and inject it into a bottle containing lyophilized powder. Tilt the bottle so that the needle touches the wall, ensuring that the diluent gradually flows down the wall (do not inject it all at once; take your time). Gently stir the solution without shaking or shaking the bottle until the lyophilized powder has completely dissolved, resulting in a clear liquid. The medication is now ready for use.
Never mix different peptides in the same syringe, as this may damage the fragile peptide molecules.
Contraindications
- Prostate cancer
- Testicular cancer
- Pituitary tumor
- Tumor that depends on estrogen for growth
- Puberty at an earlier age than expected
- Blockage of a blood vessel by a blood clot
- Ovarian hyperstimulation syndrome, abnormal enlargement of the ovaries
Injections
- Injections can be administered subcutaneously or intramuscularly using an insulin syringe.
- Disinfect the rubber stopper of the bottle and the injection site with alcohol.
- Draw the solution into the syringe and inject it slowly.
Conservation
- Keep the medicine away from light.
- Keep refrigerated (2-8°C).
- Do not freeze.
- After reconstitution, the solution can be stored for up to 28 days at temperatures not exceeding 25°C.
- After dissolution in the supplied solvent, the solution should be administered immediately.
- Keep out of reach of children.
- Do not use after the expiration date.
HCG powder that has not been mixed or reconstituted should be stored in the refrigerator, while in a dark place, below +25 degrees Celsius, it can be stored for over a month without degradation.
HCG is typically supplied with a saline solvent, which is suitable for single doses (usually in fertility treatment). If using HCG for TRT and multiple doses, the supplied saline solvent should be discarded and replaced with bacteriostatic saline. Bacteriostatic saline contains a preservative that inhibits bacterial growth, thus extending the shelf life of HCG.
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